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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TGFB2
All Species:
40.3
Human Site:
S375
Identified Species:
98.52
UniProt:
P61812
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P61812
NP_001129071.1
414
47748
S375
N
T
I
N
P
E
A
S
A
S
P
C
C
V
S
Chimpanzee
Pan troglodytes
XP_001161571
412
47357
S373
N
T
L
N
P
E
A
S
A
S
P
C
C
V
P
Rhesus Macaque
Macaca mulatta
XP_001100053
412
47296
S373
N
T
L
N
P
E
A
S
A
S
P
C
C
V
P
Dog
Lupus familis
XP_858677
414
47687
S375
N
T
I
N
P
E
A
S
A
S
P
C
C
V
S
Cat
Felis silvestris
Mouse
Mus musculus
P27090
414
47583
S375
N
T
I
N
P
E
A
S
A
S
P
C
C
V
S
Rat
Rattus norvegicus
Q07257
442
50515
S403
N
T
I
N
P
E
A
S
A
S
P
C
C
V
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511075
436
49570
S397
N
T
I
N
P
E
A
S
A
S
P
C
C
V
S
Chicken
Gallus gallus
P30371
412
47588
S373
N
T
I
N
P
E
A
S
A
S
P
C
C
V
S
Frog
Xenopus laevis
P17247
413
47621
S374
N
T
I
N
P
E
A
S
A
S
P
C
C
V
S
Zebra Danio
Brachydanio rerio
NP_919366
411
47511
S372
N
T
I
N
P
E
A
S
A
S
P
C
C
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
56.5
55
99.5
N.A.
95.4
88.9
N.A.
69.9
90
85.9
78.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
73.6
71.9
99.7
N.A.
97.3
91.6
N.A.
76.1
93.9
91.3
87.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
86.6
86.6
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
93.3
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
100
0
100
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
100
100
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
100
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
80
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
20
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
100
0
0
100
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
100
0
0
0
0
0
100
0
0
0
20
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
100
0
100
0
0
0
0
80
% S
% Thr:
0
100
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
100
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _